The beginning of the Resident Evil Revelations 2 tale sees fan favorite Claire Redfield make a dramatic return. Survivor of the Raccoon City incident depicted in previous Resident Evil games, Claire now works for the anti-bioterrorism organization Terra Save. Moira Burton, is attending her welcome party for Terra Save when unknown armed forces storm the office. Claire and Moira are knocked unconscious and awaken later to find themselves in a dark and abandoned detention facility. Working together, they must find out who took them and to what sinister end. Will Claire and Moira make it out alive and discover what’s led to them being taken to this remote island? A story of twists and turns will have players guessing the next step at every turn.

Headed for the remote prison island in search of his missing daughter, Barry Burton meets brand new character Natalia Korda, a little girl who has a strange power that allows her to sense enemies and hidden items. Using this skill alongside Barry’s proven combat abilities, players will need to alternate between the two to survive the mysterious island and find Moira. With terrifying enemies waiting around every dark corner, Barry will need to use his ammo and weapon supply wisely, in classic survival horror style.

Evolving the episodic chapter set-up of the original Resident Evil Revelations, Resident Evil Revelations 2 will initially release as a weekly series of episodic downloads beginning on February 24, 2015. Players also have the option of choosing Complete Season or Full Bundle, ensuring fans have access to each episode as it releases along with additional bonus content. Each episode in Resident Evil Revelations 2 includes Raid mode content and two full playable scenarios focused on the previously announced Claire and Moira campaign and the newly confirmed Barry and Natalia storyline.

The Deluxe Edition includes the following items:
- Barry's Commandant Costume
- Claire's Rodeo Costume
- Moira's Urban Ninja Costume
- Natalia's Lottie Suit Costume
- Raid Mode Character: Albert Wesker
- Raid Mode Character: HUNK
- Raid Mode: Album Storage A
- Raid Mode: Album Storage B
- Raid Mode: Album Storage C
- Raid Mode: Parts Storage A
- Raid Mode: Parts Storage B
- Raid Mode: Parts Storage C
- Raid Mode: Throwback Map Pack
- Raid Mode: Weapon Storage A
- Raid Mode: Weapon Storage B
- Raid Mode: Weapon Storage C
- RER2 Episode Four: Metamorphosis
- RER2 Episode Three: Judgement
- RER2 Episode Two: Contemplation
- RER2 Extra Episode: Little Miss
- RER2 Extra Episode: The Struggle
- Resident Evil Revelations 2 / Biohazard Revelations 2 (base game)